[Primary cutaneous cryptococcosis presenting with a sporotrichoid pattern in a cancer patient].

Findings from endoscopic studies in patients with esophagitis caused by alendronate are associated with chemical esophagitis, similar to that caused by acetylsalicylic acid.7 The pathophysiological mechanism involved in these cases was direct irritation of the mucosa due to prolonged exposure to the drug. The same mechanism could apply to our patients who allowed tablets to dissolve in their mouths, causing erosion due to prolonged contact of the drug with the oral mucosa. In view of the increasing use of alendronate sodium we presume this must be quite a common complication despite the paucity of cases cited in the literature. As we are aware that alendronate sodium can cause erosions or ulcerations of the oral mucosa if not ingested properly, we must consider the drug as a possible causal agent in such cases and must question the patient carefully on how they ingested the tablets.8,9